International travel and increasing cases
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Multiple choice questions
Australian Tennis Open:
a. Good idea
b. Crass commercial insanity
c. Opportunity for highly infectious VOCs to enter Australia
d. Opportunities for cross infection during travel
UK football, mass hugs and chanting in the dressing room:
a. Good idea
b. Potential source of superspreading event
c. Worst possible example imaginable at the current time
d. Illustration of one rule for the elite and another rule for us Plebs
Brazil
Manaus, Amazonas state, health system has collapsed
Severe oxygen shortages, some hospitals have run out
https://twitter.com/pamtaketom....i/status/13497413790
Rapid rise, infections from new variant
Health professionals, many people could die due to lack of supplies and assistance
Infections linked to a new variant of the virus.
Brazilian mutation
South America, Portugal and Cape Verde barred from entering UK
Argentina, Brazil, Bolivia, Chile, Colombia, Ecuador, French Guiana, Guyana, Paraguay, Peru, Suriname, Uruguay and Venezuela
(South Africa, Namibia, Zimbabwe, Botswana, Eswatini, Zambia, Malawi, Lesotho, Mozambique and Angola, the Seychelles, Mauritius)
Mutations associated with a rapid increase in cases
Grant Shapps, Brazilian variant not in the UK as far as we are aware
Next few days, then we should know
Reactivity
First detected in travellers going to Tokyo, then traced back to South America
Vaccines?
More cases all at the same time
China
Highest single-day infections since 1 March.
Cases, + 144
Hebei province, 22 million people in lockdown
20,000 rural residents sent to state-run quarantine facilities
Infection driver, asymptomatic cases in rural areas
First detection of SARS-CoV-2 spike protein N501 mutation in Italy in August, 2020.
https://www.thelancet.com/jour....nals/laninf/article/
VOC-202012/01, spreading in UK, global threat
N501Y, involves one of the six key amino acids of the SARS-CoV-2 receptor-binding domain
Angiotensin-converting enzyme 2 (ACE2) receptor
N501T detected in Italy in August
UK
https://coronavirus.data.gov.uk
Cases, + 46,169 + 45,553 + 48,682 = 3,118,518
Estimated R number
1 to 1.4
Daily infection growth rate range, of 0% to + 6% (8th January 2021)
Cases, + 48,682 = 3,260,258
Cases, last 7 days, 370,839 (down 7.4%)
Hospitalised, + 4,193 + 4,240 + 4,256 = 36,797 (3,626)
Last 7 days, 26,914 (up 34%)
Deaths, + 529 + 1,243 + 1,564 + 1,248 = 86,015
Last 7 days, 7,507 (up 50.3%)
UK death certificate deaths, 93,030
Vaccinated, first dose, 2,918,252 (Jan 15th)
Second dose, 437,977
United States
https:/covid.cdc.gov/covid-data-tracker/#trends_dailytrendscases
https://covidtracking.com/data
https://www.washingtonpost.com..../graphics/2020/natio
Cases, + 213,885 + 219,090 + 222,944 = 22,982,927
Up 4.4 % in past 7 days
National positivity, 11.9%
Hospitalizations, 128,947 (23,891) (7,878)
Deaths, 379,451
Up 19.5% in past 7 days
US, Vaccinations
First doses, 11,444,000
Second dose, 1,230,000 (0.38%)
Indonesia
Restrictions rather than full lockdowns
Masks must be worn everywhere outside the home in Jakarta and West Java, subject to sanction
EUA for the Sinovac vaccine on 11 January 2021
President Jokowi received the first vaccination on 13 January
Oxford to follow
https://www.bbc.co.uk/news/live/world-55673006
Social media influencers
Younger workers aged 18 to 59
Professor Amin Soebandrio
We are targeting those that are likely to spread the virus
Germany
Deaths, + 1,113
Spread of 2020 12 variant
Portugal
Went into lockdown overnight
Hungary
PM Viktor Orban, keen to start using China vaccine
National medicine authority